Top Definition
A disease-like state of feelings which can only be discribed as "OMG!"

Typically occurs when:
1. Ones mind is blown
2. Exciting news/gossip is discovered
3. Something unbelievable happens
Girl 1: "I'm suffering major OMG Syndrome right now..."
Girl 2: "Why? What happened?"
Girl 1: "I just found out that Mitch and Kaylee have something going on!"
Girl 2: "OMG! REALLY?!"
by C3POhbaby January 08, 2010
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