look up any word, like bootylicious:
21. O-Town
Slang for O'Fallon, Missouri. Fastest growing city in Missouri with about 40,000 people, with shops going up pratically everyday, not to mention homes.
In O-Town you can spend money, eat food or go mini golfing.
by Shaun Speers Jun 26, 2005 add a video
1. o-town
The city of Orlando. Orlando, FL
"Where's o-town? In central Florida"
by alex Aug 3, 2004 add a video
2. O-Town
Shortened term for Orlando, Florida.
We be too crunk down in O-Town.
3. O-Town
Regardless of what all these other bullshit entries say, otown is most widely known as the nickname of Orlando, Florida. Not fucking ottowa or ohio or whatever.
Homie:Yo dawg lets go to orlando, also known as O-town.
Dawg:Word.
4. O-Town
Nickname for many cities beginning with the letter 'O'. Anyone living near such a city believes their city is the only true O-Town.
Ottawa, Canada is known as O-Town.
5. O-Town
O-town is the name of the fictional city in which the animated series "Rocko's Modern Life" took place.

(thats old-skool nickelodeon for all you little kids :-P)
Supposedly located on the border between Michigan and Canada.

Rocko and Heffer live in O-town.
6. O-town
Orgasm. While it's been co-opted by proper names of actual cities and towns, it has always meant orgasm. Taking someone to O-town, will inevitably result in them showing you their O-face.
Took that girl out on a date, finally. Went for dinner, a movie, then I took her to O-town. She has the most upsetting O-face I have ever seen.
7. O-Town
a commonly used nickname for the town of Olney, MD. it is used by teenagers more frequently than any other age group.

it is occasionally mistaken for Orlando, FL. Orlando is not a definition of O-town. This is also true for other cities and towns beginning with an "O" other than Olney.
A: Yo man, you in the 301?
B: yea son. I'm in O-Town.
rss and gcal