Top Definition
Another slang word for OXYCONTIN...
Are we going to take an o-sizzle rail to our dome piece?!?!
by Susan Miller March 18, 2008

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Pronounced- "Oh-sizzle"

Street name for the prescription painkiller Oxycontin. It is a fast-growing drug that, when crushed and snorted, produces similar effects to Heroin.
Yo, got any Osizzle for me?
by smartestalex September 30, 2007

The Urban Dictionary Mug

Lotsa space for your liquids.

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The Urban Dictionary Mug

Lotsa space for your liquids.

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The Urban Dictionary Mug

Your favorite word on a white mug.

Create a mug

The Urban Dictionary Mug

One side has the word, one side has the definition. Microwave and dishwasher safe. Lotsa space for your liquids.

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The Urban Dictionary T-Shirt

Soft and offensive. Just like you.

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The Urban Dictionary T-Shirt

Smooth, soft, slim fit American Apparel shirt. Custom printed. 100% fine jersey cotton, except for heather grey (90% cotton).

Buy the t-shirt