Caucasian hip hop radio hosts who try to be with it by choosing a name associated with underground hip hop music in order to sound cool on the radio. However the name itself to regular people is actually lame.
Did you hear that O-Dog on the radio yesterday, man that guy is ill. He is dope.
1. Caine's homicidal, trigger happy friend in the 1993 movie Menace II Society.
2. To lose one's mind and become a fearless gangster. As heard in one of The Game's rap song... "it's the sequel to Menace and Oh Lord he done went O-Dog".
Now O-Dog was the craziest nigga alive. America's nightmare. Young, black, and didn't give a fuck.