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1.
A retired player
Guy 1: yo man how come you don't fuck these hoes no more???
Guy 2:I dun went O'Bryan on these hoes bruh I ain't in the game no more
by Yung Z June 20, 2013
2 3
 
2.
a square , lame , loser ; mainly used to describe a male .

yo , that dude I went on the date with was an o bryan .

by mackinkayluh April 16, 2008
3 19