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1.
One of 6 personality traits generally exhibited by women. "Number Six" is attainment of a state which involves consumption of high amounts of alcohol where a distinctive change of personality occurs (i.e, akin to Multiple Personality Disorder ) which include one losing all facades and stating the obvious faults of others with an uncanny clarity and bulls-eye accuracy.
When Number Six jumps into Becka no one wants to be around to face the brunt of her comments; knowing they'd have to look into the mirror and realize everything she said was correct.
by Shyantha December 27, 2006
 
2.
The act of defecating, urinating and masturbating until orgasm all in one sitting while on the toilet. Thereby combining peeing(#1) pooping(#2) and cumming(#3) equaling six.
I always like to start off my day by going number six.
by Mbigmizzle October 13, 2010