There is no problem between you and someone else. You're not holding anything against them and there's no need for drama.
Wathson:So you got a problem with me?
Sandra: No there ain't no pressure. You good.
Said sarcastically to an instruction to carry out something with great significance. The full meaning being "so I'm under no pressure then", when clearly you are.
"If you don't defuse the bomb millions of people will die"