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Niš is a city in Serbia and one of the oldest cities in the Balkans, and has from ancient times been considered a gateway between the East and the West.
Constantine I, ruler of the Byzantium empire (4th century) was born at Naissus, (today called Nis, Serbia)
by CrnaStrela September 05, 2005
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2
A reference to Male Genitals and Anus based on context.
ex. 1: Hey babe, wanna do it in the nis? (anus)
ex. 2: Dude, look at my giant nis! (penis or anus)
ex. 2: She totally just polished my nis (penis)
by this nis dudes December 12, 2009
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3
All these girls on my nis
by Graham Morgan January 20, 2004
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4
Hey Melissa, are you gunna get some of that 'nis tonight?
by EvilSp0rk April 12, 2006
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5
"Non-Interactive Scene"
Primarily used in the games industry to describe a cutscene where the players control of the character has been temporarily deactivated to watch a series of events.
Dude, did you see that NIS where that zombie jumps out the hallway and knocks you down the stairs? I totally papped myself.
by Gimble Shanks July 14, 2006
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6
1) of or relating to your personal space
2) an object or task that you cannot describe with English words

Other variation: nis-nis
"She was all up in my nis."
or
"We'll do the nis-nis and then get a sandwich."
by Amy D. April 25, 2005
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7
Short for the term "penis." Originated in Oklahoma along with the shortened term "Za." Nis may be used in any situation including confrontations, celebrations, and general roasts.
"Hey man, you wanna go get some za?"
"Say "za" again and I'll punch you square in your nis!"
by BrattyBB February 05, 2017
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