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It is a huge migraine (headache) that you get from seeing to many nignogs.
The effect is so severe, it can sometimes lead to "black" outs.
tom: hey jim. you dont look too good.
Jim : i know, i just came from africa, i might be suffering from a Nigraine.
by noharmony February 08, 2009
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2
The severe headache achieved from listenning to Al Sharpton complain about how every bad thing that happens to every black person is a crime against the African American culture.
Turn that shit off, man. I'm getting a nigraine from listenning to Sharpton's racist ass again.
by plplpl January 18, 2013
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