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1.
When you or something is suddenly on point as fuck. You / whatever you are referring to is on the next plane of existence / ballerdom. The urban equivalent of going super saiyan.
1: My new kicks are nigga mode.

2: James went straight nigga mode on those flapjacks.

3: Lebron went straight Nigga Mode on Durant last night.

4: Guy A: Dude I think I created a new genre of music.

Guy B: Oh yeah? Lemme hear it.

Guy B: ....

Guy B: Oh SHIT! What are you gonna call this?

Guy A: Nigga mode.
by mike67256346 December 30, 2012
 
2.
When someone is looking really fresh. Everyone is paying attention to them
Last week my boy Brett Smith was in nigga mode, he was getting a lot of girls that night
by niggamodedawg November 25, 2009