Top Definition
New Castle Fever is a serious medical condition in which a female becomes attracted to a male from New Castle, Pennsylvania. The disease is characterized by a strong desire to be around the New Castle male (hallmark symptom), flushing of the face, and an acute fever. New Castle Fever is becoming increasingly prevalent, with the highest incidence in Western Pennsylvania and Eastern Ohio. Treatment involves either immediately and completely discontinuing the interaction with the New Castle male or pregnancy.
I have been hanging out with this kid from New Castle and I am certain that I want to give birth to his baby...I must have the New Castle Fever.
by NugeBalls January 28, 2011

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