To fail in a spectacular fashion while attempting to act smooth or cool, i.e. sending your allergy suffering grandma to the hospital with a bouche of flowers.
Jake: "Dude check it out."
Lund: "No way! Zach's hittin on Darby? How's he doin so far?!"
Jake: "Well he just asked her how far along she is."
Lund: "The fuck?! Since when is she pregnant?!"
Jake: "She isn't"
Lund: *Sigh* "What a Neuf."