Top Definition
Nespelem aka nasty town; A reputation for producing some of the best looking tribal members who cannot keep thier hands to themselves, aye cousin!
That girl is fine, if only she wasn't Nespelem!
by Shaka-ka July 04, 2008
1 more definition
Inbred, Drug Addicted, Racist, Ignorant, Gang Affiliated and probably driving drunk.
The Leading Cause of Death in Nespelem, Wa is Drunk Driving. But Most people call it Karma.
by Patience-Is-A-Virtue February 21, 2011

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