Top Definition
The intense mission of doing a female in her rear end and then pulling out, placing some ecstacy on her asshole, and then pushing it in with your penis during reinsurtion. Mystery plug!
Robert pulled a Myster-E-Plug on his girlfriend during anal sex and minutes later laughed as she tried to figure out why she felt as good as she did!
by Brotha Flip August 31, 2007
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