Top Definition
Typically refers to a woman who is extremely talkative and enjoys getting reactions out of people.. For example: May make comments about butts of all sizes, make practical jokes (e.i. keeping someone's hair), talk about sensual content, or even do random things such as sensing demons or look for Tinker Bell. A Muzie is also OCD on random things, some examples are: shaving, cleaning ears, cleaning rooms, and anything that has to do with cleaning. Essentially she is out of control. However, she is typically loved by all!
Woah! She's a muzie!
by eugene:) March 04, 2012

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