2. The ex-guitarist of heavy metal band Metallica for the first album, who was fired over an incident involving James Hetfield in 1983 and went on to found the much better but far less popular band Megadeth.
2. Dave Mustaine is a far superior guitarist and vocalist to James Hetfield.
Named for Dave Mustaine, vocalist/guitarist for Megadeth; derived from the song "The Mechanix", in which Mustaine for no reason yells "FUCK YEAH!" near the end.
"Well, she was talking about her sick cousin, but his team scored a goal and he just pulled a mustaine."
guy 1:why are you washing your face?
guy 2:trying to wash off that mustaine you gave me last night
guy 1:dont worry about it, just let it rust in peace.
guy 2:why do you have to draw a mustaine on me every night? how about you know, put a plug in it?
Alternate: Mustained, Adverb. To have been cast asside by one's peers, to have been excommunicated, or fired.
Origin: Dave Mustane- former guitarist for Metallica, who was famously kicked out of the group for being an insufferable ass.