Top Definition
When you observe either an appearance or a behavior of someone that really bothers you and you can't quite find the right word to describe this annoyance - Calling some a Muopsies (adjective) or naming someone a Muopsies (noun) is a combination of all of the derrogatory words you were thinking of into one.....perfect.....word
That Muopsies wearing the striped shirt is holla'in at your girl!!

Don't be such a Muopsies Jones.

Only a real Muopsies would not drink this liter of vodka.

by PC so Greasy June 20, 2007

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