The bump or bulge seen when a man wears tight pants.
"Is that a moose knuckle I see; or do you have a raisin in your pants?"
by the dude1963 April 20, 2013

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A woman with big pussy lips - in small clothing looks like she's got a mans package.

Also refers to an ugly vagina. The more beat up the vagina is the more it looks like a mooseknuckle. Loose vagina
Aaron: does yana have a cock?

Rob: naw, shes got some huge coochie flaps aka Mooseknuckle

Aaron: wtfh??

Rob: her shit is loose - beat the fuck up!

Rob: her shit is as big as her forehead

Aaron: word
by Nontoxic March 31, 2010

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The guy version of cameltoe.
Hey... look at that guys, Moose Knuckles... Gross!
by Nastynae June 09, 2009

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When a man has a camel toe because he's wearing something really tight.
Mark proudly showed off his huge moose knuckle in his red bike shorts.
by charlesramsey August 06, 2013

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A male style of a cameltoe
Nick was watching porn and he stood up and has a mooseknuckle
by Tugginmypudda September 04, 2010

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when an obese lady has camel-toe
that camel to is so big its like a moose knuckle
by bob joe's May 07, 2012

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Male version of a camel toe; nad splitter ; testicle wedgie.
Damn, did you see the moose knuckle on that old geezer? If his pants weren't hiked up to his armpits them nads would be dragging the dirt.
by ryder69 October 11, 2014

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