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1.
A girl of unsurpassed beauty and charm who, like the work of art of her namesake, has a stamp of "do not touch."
She's positively gorgeous, but doesn't date: a regular Mona Lisa.
by iantheman September 19, 2007
159 38
 
2.
A pretty girl who does'nt like to smile. Usually caused by a traumatic upbringing and/or bad relationships where she was taken for granted. Because of what she's been through, she does'nt realize how truly attractive she is or does'nt consider herself attractive anymore. A prime example of damaged goods.
Guy 1: Why does'nt the cutie that works at Starbucks smile more often? A pretty girl like that should be smiling all the time.
Guy 2: She's a mona lisa, bro.
Guy 1: Well, there's definitely a special place in hell for her ex boyfriends.
by GhostHunter September 06, 2005
128 60
 
3.
Leonardo da Vinci's masterpiece.
Steve: "what did that guy do with the mona lisa after he stole it?"

Bob: "He jacked off to it"
by mark101 June 11, 2008
82 40
 
4.
1. a painting by the famous artist Leonardo da Vinci; perhaps the most well-known painting in the history of art

2. a girl whose emotions are absolutely unreadable. These girls are the hardest types to understand.
Many painters adore the Mona Lisa, da Vinci's greatest work.

My girlfriend is such a Mona Lisa. I can't ever tell whether she wants to shoot me or do me.
by J Filthy Money June 09, 2010
29 9
 
5.
A painting in the Louvre.
Guy 1. I took my girlfriend to the Mona Lisa yesterday

Guy 2. You took her for a piercing where a beauty mark should be? Stroked her with such skill that she moaned?

Guy 1. No, you muppet, it's a painting.
by Bladebond March 03, 2007
40 27
 
6.
A girl that always has the same facial expressions, so that people can never tell what she is really thinking or feeling.
A: That chick seems pretty nice. I don't understand her though.
B: No, man, she's a Mona Lisa, you'll never understand her.
by Notrurwords November 12, 2011
12 7
 
7.
verb: "to mona lisa it"

To Mona Lisa it, or "pull off a Mona Lisa," if you will, is to take a dump in such a way, that when you wipe there is no crap on the exterior of the anus. Thus, after the first wipe, the toilet paper remains pristine white, pink, or whatever the original color. Congratulations, you've painted the perfect picture on the toilet paper: You just mona lisa'd it.
Dude, I just took the most solid shit. I Mona Lisa'd it. What a relief to be green and save a little extra tp.
by Reeseyfon August 27, 2010
15 19