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1.
Slang for mother fucking ugly.
My eyes! That girls mofugly, just look away!
by benjeeeboy March 05, 2004
 
2.
Mother-F*ckining Ugly
"She's Mo'ugly!"
by Trevor November 07, 2003
 
3.
Politically correct way to say someone is ugly beyond reason.

Word commonly used when Aunt Gerdie who is 75 and a Jehova Witness (so you cant definetly noy curse in front of her)gets home with her grandaughter.
"Your mofugliness precedes you'
by Da shiznit mom December 28, 2004
 
4.
More fucking ugly
damn, that bitch is mofugly 'n yo momma
by Anonymous August 29, 2003