To be "Mode One" with someone means to be extremely candid and provocatively honest, particularly as it relates to someone expressing desires, interests, or intentions related to sex.
"Girl ... that man approached me, and he was very Mode One with me. I was shocked at some of the things that came out of his mouth!!"

"I met this woman last night, and she was totally Mode One with me. I wasn't talking to her for more than two or three minutes before she asked me could she give me a blowjob..."

"I was at this house party the other day, and this guy was being totally Mode One with these women. As soon as he approached them, he just started asking them about their sexual fantasies, and sexual preferences. I couldn't believe how bold and sexually straightforward he was with his language..."
by Alan Roger Currie July 15, 2006

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