Top Definition
A mitsume is the biggest bitch in the world. She becomes your best friend and then dates the man\woman you are in love with, pretending that she had no clue you loved them. Another thing Mitsume's like to do is to betray you when you're going through a tough time with your partner.
your partner: "I don't even want anything to do with him anymore."

Mitsume: "Yeah, I don't even consider him my friend anymore."
by Triorio July 17, 2009

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