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1.
The act of vomiting, urinating, then defecating on a womans pussy and stirring it up with your dick, creating a kind of salad inside her.
The only good thing about getting the flu every once in a while is that Mary let's me give her the old Mississippi Salad.

I now walk around shirtless in December so I don't miss the opportunity.
by Dont Ask... Man March 02, 2010
4 4
 
2.
When a guy takes a dump, then a piss, then pukes into a girls vagina and stirs it up with his cock.
"i gave a mississippi salad to jenny yesterday and samantha ate it... heard they both had syphilis"
by arseman January 25, 2008
4 18