man on fire; an angry guy. It's a biblical name; he was one of the guys that got put into the burning oven, but did not burn due to God protecting them. Under the book of Daniel in the Spanish translated bible.
Yo, that Misael just went in there and kicked that guy's ass.
by VirtuousDemon21 February 03, 2010
1 more definition
according to Canadian slang, misael Me-Sai-El means to impregnate.
I'M GOING TO MISAEL YOU FAGGOT! I DON'T CARE IF YOU'RE A GUY.
by Canadian Slang April 27, 2011