Top Definition
A condition where the person at hand can't resist rooting for the underdog. Usually accompanied by a life of high dreams and much failure.
Dude, why does Ronnie always pick the Timberwolves on 2k11? They suck!

It's not his fault, they guys got a serious case of Mighty Ducks syndrome.

Oh. I see. Poor Ronnie.
by Addedoo May 31, 2011

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