Top Definition
The astonishing occurrence when a fan-favorite contestant on a talent competition - like "American Idol", or "So You Think You Can Dance," in which the viewer votes for the winner - is voted off the show, more specifically before the finals of the competition. Abbreviation MDS
Lil'Kim came down with a bad case of Melinda Doolittle Syndrome on "Dancing with the Stars" this season.

I wonder who's gonna catch MDS this season on Idol.
by J-Breezey May 22, 2009
5 Words related to Melinda Doolittle Syndrome

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