Top Definition
A state of realization that one is even more depressed when drunk than when sober.
Person A: "What's the matter?"
Person B: "I'm suffering from melancholicolica."
Person A: "You know that drinking is bad for your depression."
Person B: "Yah, I know."
by Paige K.A. Fletcher October 12, 2008
5 Words related to Melancholicolica

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