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1.
A play on words with Senator John McCain's last name, replacing CAIN with SHAME. This is one of many neologisms which have been coined as of late concerning McCain's name, as well as with Obama's name -- depending on one's political preferences with either presidential candidate.
In the 110th Congress, Senator John McShame has missed 62.6% of all Senate votes -- more than any other senator!
by lenvus July 17, 2008
 
2.
what you feel eating your super sized fast food value meal in your car alone while still in the restaurant parking lot
I grabbed some lunch at McD's and leaving the drive thru I totally saw Al eating in his car. He looked like he had some McShame going on.
by eating disorder July 07, 2009
 
3.
The first McDonalds burger you have in the new year having made the resolution to lose weight.
Tiffany: "Mmm... this is so good"
Sam: "Weren't you trying to lose weight in the New Year"
Tiffany: "Yeah, this is my McShame burger"
by topgear123456789 December 31, 2013