nickname for marijuana; many singers use this in their songs
"Last dance with Mary jane, one more time to kil the pain..."
-Tom Petty
by Mr. Ed March 08, 2005

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Top Definition
Mary Jane is a different name for Marijuana. Also a song from Rick James which really explains it well.
Lyrics from Mary Jane sung by Rick James...

I'm in love with Mary Jane.
She's my main thing.
She makes me feel alright.
She makes my heart sing.
by R 2 J Through K January 08, 2005

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Another word/phrase for marijuana, It is no particular type of marijuana, just a slang word for it in general. Also can be shortened as just Mary, not Mary Jane
I was Smokin' that Mary-Jane Yesterday.

Mary got ya paranoid.
by G-Fo March 03, 2005

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Slang for marijuana. It originates from the Spanish language. Literally
Mari-Mary
Huana/Juana-Jane
"Let's smoke that bowl, hit the bong,
And then take that finger off of that hole,
Plug it, unplug it,
Don't straaaain, I love you Mary Jane,
She never complains, when I hit Mary,
With that flame, I light up the cherry,
She's so good to me, when I pack a fresh bowl I clean the
screen,"
-Cypress Hill; Hits from the Bong; Black Sunday
by azrael March 23, 2005

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another term for marijuana
I love that MaryJane
by LIMME September 17, 2003

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1.Spidermans lover

2.Marijuana
1. spiderman man loves maryjane watson (the girl)

2. spiderman loves maryjane (the plant)
by SpIdUrMaN January 20, 2005

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slang for weed. mary jane is the literal english translation for marijuana.
mary=mari
jane=juana
Me encanta mi marijuana.
(I love my mary jane.)
by Amy O'Connor March 25, 2007

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