Top Definition
The act of making stupid mistakes over and over (usually at the same point) while trying to perform what should be a simple task. This most likely happens when doing things in a rushed manner.
Mario Brothers Syndrome:
Basically, in the original Super Mario Brothers for the Nintendo Entertainment System, trying to get through certain worlds hastily causes errors on the players part. Like hitting a turtle sideways and dying instead of jumping directly on it.
by Trace Faulkner September 03, 2008
5 Words related to Mario brothers syndrome

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