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1.
Occurs when playing Mario Kart 64. Occurs when you gloat about having overtaken someone on multiplayer, and as you race away to the finish line to take the coveted title of "dude", you find yourself hit by a red shell and you quickly go from 1st to last.
Guy 1: HA! You guys suck! I'm about to hand out some PAINbow Road! WOOO....wait? RED SHELL?! NOOOO!!

Guy 2: That's Mario Karma for you.
by TheMadFelcher March 29, 2010