The beginning of the week: For work and/or school resulting in depression is a genetic condition that is triggered either spontaneously or from a significant amount of emotional pressure, associated with it being Monday!
Manic Monday....sigh...4 more days until the weekend.
A continuation of the days of the week related to typical alcohol consumption. i.e. Screwed Up Sunday, Manic Monday, Twisted Tuesday, etc.
Bob: You ready for Manic Monday?
Joe: I've always been more of a Thirsty Thursday person, but I'm up for a new challenge!
An unemployed workers first day back at a different position, with less pay.
Man if i would have known i wouldn't even get my own cubical, i would have slept in on Manic Monday and continued to collect unemployment checks.