Another meaning is basically the NES game. This was a classic, one of the best NES games around, with lots of hilarious humour and mind-melting puzzles. The game revolves around the story of a weird mansion where a crazy scientist and his loopy, roleplay lovin' nurse wife captures a dumb blonde cheerleader girl, and you have to play as her boyfriend and two of his friends to rescue her from the mansion.
Good fun, jam packed full of crazy scientists, senile, kinky elderly nurse bitches, radioactive purple slime, punk-rock music, exploding hamsters, dead cousins and wax fruit munchin', Pepsi gulpin' "tentacles".
by Ooh_Edna! May 16, 2004
1 Word related to Maniac Mansion
A crazy-ass low-income dwelling where shit's always happenin'and the police are there so much they should set up a mini-station in the motherfucker!
435 13th Street,San Diego,CA 92101 Near Gaslamp Liquor store where people cash they checks,booze up, beg,scam and tweak and walk in da middle of da street.They use da sidewalk for a toilet and bed at the same time!
by 51/50 October 27, 2003

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