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8.
originally used in context to video games in which, if a player's character was on the verge of death, one would shout to the player to "man-up." has elvoved into meaning "stop being a big wussy baby."
Dude, stop crying and man-up! (or)

Tony: Dude, can we take a break from the Wii? My hands are cramping?
Ralph: Man-up, wuss!
by SUPER-AWESOME-MAGIC November 29, 2006
 
9.
An uplifting imperative, derived from the saying "be a man about about it" - to grow a pair, to stop being childish, to stop complaining etc.
This saying can be used in many situations.
1) 'C'mon Gareth, man up! There's no time for tears in this day and age.'
2) After some hurtful comments from a female colleague, Gareth turned to Jimmy for advice. Jimmy said "Grow a pair and man up!"
3) 'Gareth is acting so childish - he needs to man up'
by meandmyfufu January 26, 2011
 
10.
to build up enough courage (usually for men) to face adversity and responsibility
When someone man-up its shows maturity and increases respect from society.
by Gerard Irick April 16, 2010
 
11.
When a man is being a little sissy boy blaming others for his problems and lying about the truth.

Action verb: To Start acting like a real man.
Dude, you need to Manup to the truth and accept responsibility for your actions.
by joyle March 27, 2008
 
12.
when a pansy-ass MAN is acting out of his job description and needs to be put into place.
"...stop acting like a little girl and man up, fool."
by Marvin June 27, 2003
 
13.
adv; mans up, manning up, manned up.

1.To man up: Its time for you to man up for your baby girl.

2.To be manning up: he manned up once he saw the one.

3.To have manned up: he manned up for his son in the past.
1.Did he man-up, or fess-up to his moma!?

2.Today I might be manning-up, for class.
3.Get up to my level of happiness, before you leave.
by RB. 865. January 25, 2014
 
14.
v. To act in accordance with established masculine roles in a given situation, implying courage and responsibility. Usually used in the imperative, the term is a favorite of police who want suspects to incriminate themselves. Ironically, advice to 'man-up' is usually followed by a promise that it is the least painful alternative.
You signed for a package full of weed, now you need to man-up, and admit that you knew what was in it. It'll go easier for you with the judge.
by tom ballard, esquire March 02, 2009