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1.
The affliction of not seeing something even when it is right in front of your face.
When a man looks in the pantry and cannot find the replacement mayonaise, he has man disease.
by marshalynn January 09, 2011
 
2.
Were either you are looking at something but do not see it or you always have to be right.
"Honey, does anything look any different?"

"Um...no?"

"Seriously! Typical man disease."
by Captain DRock April 25, 2010