A slang used by only the coolest of cool meaning the opposite of "Benedryl" which is another word used only by the coolest of cool. Mafooba means something awesome, good, or whoop ass. Or a word used by gamers to refer to ownage.
"Those new shoes are freaking mafooba!" or "I just went mafooba on your hiney with a knife!"
by Communists July 29, 2008
1 more definition
The secondary English word for good, superb, the opposite of Benadryl. Striving in excellence, absolute perfection.
He is so mafooba I could poo out diarrhea in a public bathroom and smear it on the walls to write out letters!
by Faggatron5 July 29, 2008