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1.
MPU
MPU (mobile party unit). A core group of partiers who always party together, week after week, regardless. They MPU consists of only the most intense individuals who stay true to partying.
Joe: So the MPU rolled up to Gary's house last night.

Bill: Dayumm, those guys are hardcore

Joe: Fuck yeah they are, they left at noon the next day and had a box of bagel bites and Keystones for breakfast.
by P-hil G March 01, 2009
 
2.
MPU
Male Parental Unit refers to the husband of the married girlfriend for which you are having an extramarital affair with.
What is your alibi for the MPU this week? I have time to hook up. The MPU just took the kids to the ballgame.
by icarusymwv January 21, 2010
 
3.
M.P.U. is an acronym for Mounted Practice Unit. This unit contains a dildo with a shoulder mount that surounds the head. The M.P.U. has a motor that moves the dildo back and forth. The point of this device is to practice oral sex with a guy.
I suck at giving head, I need to go home and practice with my M.P.U.
by A-ron123 October 31, 2006