This describes a substance that is particularly strong tasting or bitter (like lemons or popping candy). the phrase comes from the face pulled when tasting such substance, tabs in this case being a slang word for 'ears'. (also, in Derbyshire this phrase would be pronounced 'meck yer tabs laugh')
Man 2' Raw Lemon'
Man 1' blimey mate if you suck on that much longer, that'll make your tabs laugh'.