Derived from the Latin words "louse" and "sea": 1. To screw one over. To suck away one's soul and reason to live. 2. To have much "louse".
1. Mathaniel's ponytail got caught in a blender while making a strawberry smoothie for a friend he secretly hated. Damn, that's lousey.
2. A large truck-making powerhouse takes away your icecream pizza parties. Those lousey bitches.
3. That dude is covered in louse. He's lousey.