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1.
1. Noun

Year after year their football program fails to impress as they lose to Rancho Cucamonga High School. Also has a large concentration of homosexuals and snobby blondes.

2. Verb
Commonly used to describe terrible beatings and embarrassment.
Man did you see that Los Osos High School! What a terrible thing to happen to someone!
by Driftkid November 14, 2011
 
2.
The ghetto white people high school in Rancho Cucamonga Cali. They tend to pepper spray other high schools. And have a lot of drugs.
Hey did you hear what happened at Los Osos High School? Etiwanda doesn't look so bad!
by NotAtTheE October 25, 2013