Top Definition
A condition that can be easily identified by subjects overuse of lol, lmao, rofl, and other variations. As of yet there is no cure.
Person 1: "Lmao, haha, lol, rofl that is soo funny!"
Person 2: "Are you having a seizure?"
Person 1: "No I was diagnosed with Lolz Disease."
by Veronica Karella October 31, 2007
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