When a little boy hits puberty and ejaculates for the first time. His expression is a little something like this: 0.o
Jesse: I think my son had little boy syndrome today!
James: Why is that Jesse?
Jesse: he looked a little something like this 0.o
by Pwned XP June 01, 2010
Top Definition
a man's momentary regression back to a childish nature whereby he purposely goes out of his way to piss people the fuck off (ex. if hes having a bad day, then everyone else has to also)... like a little boy
person 1: "frank's been pissing everyone off all day just because hes in a shitty mood."
person 2: "oh, hes got the little boy syndrome."
by faancyface December 24, 2014

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