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2.
Something you say to statements that are false with the intent of harming your good name, or further damaging you already bad name
A: I heard you slept with that fat girl Carol

B: Lies And Slander

A: So you didn't?

B: No.
by NewEspi September 24, 2008
 
1.
1.) A phrase used to signify that whatever has just been said is untrue and/or an insult to someone/something.

2.) A phrase commonly used in a humorous fashion as a way to deny an accusation.
1.) So (insert politician's name) promises to lower our taxes, improve healthcare, and protect our Constitutional rights? Lies and slander!

2.) Suzy: "Did you eat the last piece of pie?"
Pete: (w/ crumbs on face) "Lies and slander!"
by Comrade Sami November 11, 2008