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1.
Used as a nicer/cleaner way of saying Fuck off.
Man#1:can I borrow your math answers?
Man#2:Lick me u whore.
by Sameer April 24, 2005
 
2.
Phrase used to dismiss, reject, or condescend.

Popular slang phrase used in late 1980's. Originated from students at Linganore High School in Frederick, MD after viewing the film "The Exorcist".
"Can you quit talking? I'm on the phone."

Lick Me you bitch!
by Sir Hardin Thicke August 28, 2007
 
3.
When you want someone to lick you. Pretty straight forward guys.
Person 1: Hi.
Person 2: Lick me.
Person 1: What?

Person 2: Lick Me.
Person 1: What you mean?
Person 2: I want you to lick me. like with your tongue. Now.
by JohnAginDawson October 02, 2014