In the year 2000 Lareine suffered a horrible breakup. With the departure of drummer Machi soon followed guitarist Mayu and bassist Emiru. Kamijo tried to carry on as a soloist releasing the album Scream with his own work but still under the band's name as the music was played by the former members. After the release of already scheduled for release albums Reine de Fleur and Etude Kamijo released the album Crystal Letos as a message for the other members (Mayu, Emiru, Machi). He succeeded in getting Mayu and Emiru back. Machi however did not wish to return.
In early 2001 Larine was put on hold. Kamijo and Mayu joined the band New Sodmy later in the year. Emiru went off and formed his band Ribbon. Machi had gone off to form his own band called Chantons L'amour (not to be mistaken by the band's legendary tour of 1999). After New Sodmy's first concert Mayu left the group after an arguement with one of the members (although which one has never been mentioned a large amount of fans point to Kamijo).
After the disbandment of New Sodmy in late 2002 Kamijo was contacted by Emiru who stated he had felt a longing for Lareine recently. Inviting both bassist Emiru and guitarist Mayu to his home Kamijo managed to convince them to join him and set Lareine back in motion.
On March 1st of 2006 Kazumi left the group. Lareine has since searched for another drummer and contacted Machi. As of september 16th of 2006 Lareine will be starting again with its original lineup. Kamijo(vocals), Mayu(guitar), Emiru(bass), and Machi(drums).
On the date of the Chantons L'amour concert Kamijo lost his wife Audrey to leukemia. During the performance of the song Tsukiyo no Kageki (Opera of the Moonlight) Kamijo can be seen holding a doll made in the liking of his wife. He'd previously received a call of her death the night before and had asked for the creation of the doll four months prior when Audrey had informed him of her unfortunate fate. During the performance of Tsukiyo no Kageki Kamijo can be seen on brink of tears caressing the doll as though it were his beloved Audrey and Mayu, Emiru and Machi are all bowing their heads (for Emiru this is unusual as he usually puts forth a tremendous amount of energy on stage). Mayu's fingers seem to move faster on his guitar and the only times he actually looks up his eyes are clouded with unshed tears. Machi's drumming is softer than in other songs. The album "The Last of Romance" was released with a dedication to Audrey and last words from each member for her, Kamijo's being an astounding full page long. To this day Kamijo has not been able to forget Audrey as he has stated in interviews. At two particular interviews he was unable to contain himself and cried when asked about his love life. He was asked if had a girlfriend and he had quickly said no but then could not catch himself as memories of Audrey flooded his mind.
In 2000, 3 members decided to leave. Emiru wished to leave due to musical differences; after his decision, Machi also decided to leave for the same reason. Mayu, feeling that Lareine would not be the same without them, also withdrew from Lareine. After their last concerts together, the "Miss Carmila" tour in 8/2000, Kamijo continued alone, still using the band name "Lareine." He released 1 single ("Grand Pain") and 2 albums ("Scream" and the fan club-only version "Vampire Scream"). After a concert at Shinjuku Liquid Room in 12/00, Kamijo took some time off and joined the band New Sodmy for a year and a half.
On March 26 2003, Lareine officially resumed activities with a concert at Shibuya AX. Emiru rejoined, and ex-Ribbon drummer Kazumi became a member. Former New Sodmy roadie Motoki (later of D'AIR) played support guitar. That same day, Lareine released a new version of "Saikai no Hana" and the 2-CD compilation of their indie work "Reine de Fleur." Mayu rejoined Lareine in May 2003. They released a series of 3 mini-albums -- "Majesty," "Knight," and "Princess" -- in the following year. As a present to fans, Lareine recorded some music box versions of their songs which were sent as a free CD to fans who sent in the coupons from those 3 mini-albums. In March 2004, the music box versions received general release as the CD "Crystal Letos."
On March 1st 2006, Kazumi left Lareine. The band noted in an e-mail message to fans about his departure that he'd wanted to leave on March 26th when they usually played their "Romance Kakumei" anniversary concert, but that the others decided to change the concert to a different day that year because they didn't want that happy anniversary to become a sad one. Lareine's concerts for the rest of 2006 were with Kazami (ex-Clavier) on support drums. There has been no news of Machi in several years. In May 2006, Kamijo made a solo appearance at the American convention "Fanime". Lareine as a band never performed outside of Japan.
Lareine officially stopped activies on October 31st, 2006. For several months, Mayu had not been in contact with Kamijo and Emiru, and the band was unable to continue with neither a drummer nor guitarist. Lareine played their last concert with Kazami on support drums and Hizaki (ex-Sulfuric Acid) on support guitar.