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An unpleasant, cruel, or maliciously insane woman. The female incarnation of Evil Itself.

Often used to refer to female math teachers.

Taken from the the unpleasant character in Shakespeare's Macbeth.
Student: Who do you have for math next semester?
Friend: Mrs. Whitman, you?
Student: Roberts. Wait--Did you say Whitman?
Friend: Yeah, why?
Student: Watch out, man. She's like freaking Lady Macbeth.
by Lady Chevalier May 11, 2005
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The vengeful act of crapping on a lover's chest while they sleep.

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2
What you call someone when they constantly wash their hands.
Kayleigh - *Washes hands for 50th time in 4 hours*
Me - "Woah! Lady Macbeth, get out the sink!"
by DEllis April 23, 2006
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when you get someone's cum on your hands and no matter how much you wash you just can't seem to get that damn smell out
Ugh, I have a total Lady Macbeth going on after that hookup, even though I showered twice!
by doorfish July 01, 2010
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4
Literature's biggest douche. The bitch is fucking crazy.
Lady Macbeth is fucking crazy.
by Harley Austin January 18, 2012
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Soft and offensive. Just like you.

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