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1.
LYFAO; LAUGHING YOUR FUCKING ASS OFF
George said it was so funny that you were LYFAO, dude!
by Mia.dancer January 26, 2009
 
2.
LYFAO (Laughing Your Fucking Ass Off) is commonly known as a contrapositive of LMFAO (Laughing My Fucking Ass Off). Except that the other person is saying "LMFAO on YOUR side!!!"

(ProTip: They meant "LYFAO")
Passenger: "Why are you driving on the left side of the street?"

Driver: "OMGRLY? LMFAO!"

Passenger: "LMFAO on YOUR side! I mean...LYFAO!!!"
by DickDangerous September 29, 2012