Similar to "Blue Balls," this is the phenomenon that occurs when a fan of the show LOST is anticipating the next episode or the outcome of the most recent pre-commercial cliffhanger, only to be let down when they discover that their questions are left unanswered.
Brian: "I thought for sure that they were finally going to reveal the Man In Black's real name."
Melinda: "Sounds like you got a case of LOST Balls!"
When you are about to do something and suddenly lose your nerve to complete the task at hand.
I was about to jump over my moms house on my bike but I lost balls at the last second when I realized that I don't have health insurance.