It stands for Laugh Out Loud For Real and is used when something is so funny that you actually laugh out loud instead of just typing lol.
dude that was so funny i LOLFR
by Holic February 22, 2007
When chatting, to actually laugh out loud, whereas lol has the connotation of just being mildly funny.
What do Wal-mart and Catholic priests have in common???

Wut?

They both have little boys pants half off...

lol fr!
by Hung Lowe March 10, 2008
Laugh Out Loud For Real
lolfr
wow. that was really funny.
by hyrum December 14, 2004

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