Top Definition
LMFAOIS

Internet slang term. An abbreviation of "Laughing My Fucking Ass Off Into Space"

Reserved for rare times when you really laugh hard out loud at something that is very hilarious.
Guy #1 said, "Dude, I got a fucking STD from a virgin chick! It's bullshit! Bullshit, I say!"
Guy #2 simply said "LMFAOIS!"
by Digitus February 21, 2008

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